Author

Britta Knapp

Novartis (Switzerland)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Adriano AguzziiD· 1 shared Alexandra Hinniger· 1 shared Andrea ArmaniiD· 1 shared Anna SpinelliiD· 1 shared Ashutosh DhingraiD· 1 shared Benedikt GoretzkiiD· 1 shared Catrin Swantje MülleriD· 1 shared César Fernández Fernández· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Adriano AguzziORCID

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Author profile →

2 papers

Recent·Most cited

Structural basis of dual BACH1 regulation by SCFFBXO22 and SCFFBXL17

Benedikt Goretzki, Maryam Khoshouei, Patrick Penner, Christine Stephan, Dayana Argoti, Nele Dierlamm, Jimena Maria Rada, Sandra Kapps, Zacharias Thiel, Merve Mutlu, David Furkert, Catrin Swantje Müller, Felix Freuler, Simon Haenni, Laurent Tenaillon, , César Fernández Fernández

This study elucidates how BACH1 is regulated by SCFFBXO22 and SCFFBXL17 through structural changes in FBXO22 and modifications in BACH1's BTB domain, affecting its ubiquitylation and stability.

bioRxiv · Jun 3, 2024 · PreprintBiophysics

Robust and Versatile Arrayed Libraries for Human Genome-Wide CRISPR Activation, Deletion and Silencing

Jiang‐An Yin, Lukas D. Frick, Manuel C. Scheidmann, Tingting Liu, Chiara Trevisan, Ashutosh Dhingra, Anna Spinelli, Yancheng Wu, Longping Yao, Dalila Laura Vena, Britta Knapp, Elena De Cecco, Kathi Ging, Andrea Armani, Edward J. Oakeley, , Adriano Aguzzi

The paper constructs genome-wide CRISPR libraries for gene ablation, activation, and silencing with high efficacy and reports novel gene regulators and modifiers.

bioRxiv · May 25, 2022 · PreprintGenomics