Author

Bruno Afonso

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Drosophila· 2 Organism:C. elegans· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Albert CardonaiD· 2 shared Aravinthan SamueliD· 2 shared Claire EschbachiD· 2 shared Marta ZlaticiD· 2 shared Akira FushikiiD· 1 shared Anastasiia Evans· 1 shared Ania Pino-Querido· 1 shared Anna VerbeiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Albert CardonaORCID

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3 papers

Recent·Most cited

A multisensory, bidirectional, valence encoder guides behavioral decisions

Claire Eschbach, Katrin Vogt, Bruno Afonso, Nick Polizos, Stephanie Dancausse, Anastasiia Evans, Anna Verbe, Kun Wang, Matthew Berck, Aravi Samuel, Mason Klein, Albert Cardona, Marta Zlatic

The paper identifies a neuron in Drosophila larvae that bi-directionally encodes valence and guides navigation based on sensory cues.

bioRxiv · Sep 26, 2025 · PreprintNeuroscience

Circuits for integrating learnt and innate valences in the fly brain

Claire Eschbach, Akira Fushiki, Michael Winding, Bruno Afonso, Ingrid V. Andrade, Ben Cocanougher, Katharina Eichler, Ruben Gepner, Guangwei Si, Javier Valdés-Alemán, Marc Gershow, Gregory S.X.E. Jefferis, James William Truman, Richard Doty Fetter, Aravinthan Samuel, , Marta Zlatic

The paper maps convergence neurons in Drosophila that integrate innate and learned olfactory drives to mediate action selection.

eLife · Nov 10, 2021Peer-reviewedNeuroscience

Partial selfing eliminates inbreeding depression while maintaining genetic diversity

Ivo M. Chelo, Bruno Afonso, Sara Carvalho, Ioannis Theologidis, Christine Goy, Ania Pino-Querido, Stephen R. Proulx, Henrique Teotónio

This study shows that partial selfing reduces inbreeding depression while preserving genetic diversity in C. elegans by purging deleterious alleles and maintaining adaptive variation.

bioRxiv · Oct 27, 2017 · PreprintEvolutionary Biology