Author

Bryce David Colon

Purdue University West Lafayette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Chris Rochet· 2 shared Jean-Christophe RochetiD· 2 shared Jennifer A. Hensel· 2 shared Alicia N. Scott· 1 shared Alicia Nicole Scott· 1 shared Apostolia TopaloudiiD· 1 shared Aswathy ChandraniD· 1 shared Aurélie de Rus JacquetiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Chris Rochet

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Author profile →

4 papers

Recent·Most cited

Patient-derived tau-seeded human neuronal chimeras recapitulate mature Alzheimer's tau pathology and uncover human-specific neuronal vulnerability

Yanru Ji, Purba Mandal, Jiahui Liu, Wen Hu, Bryce David Colon, Changlin Wan, Raymond W. Pan, Dongkai Guo, Lijia Zhang, Xingjian Gu, Yang Yang, Kun Huang, Riyi Shi, Chao Qi, Chongli Yuan, , Ranjie Xu

This study develops a human neuronal chimera model to study Alzheimer's tau pathology, showing human-specific vulnerability and recapitulating mature AD features in vivo.

bioRxiv · Jul 9, 2026 · PreprintNeuroscience

Phosphoproteome modifications and cortical circuit dysfunction are linked to the early-stage progression of alpha-synuclein aggregation.

Sayan Dutta, Jennifer A. Hensel, Alicia N. Scott, Rodrigo Mohallem, Leigh-Ana M. Rossitto, Hammad F. Khan, Luke A Diehl, Teshawn Johnson, Bryce David Colon, Jacob E. Gold, C G Ferreira, Jackeline F Marmolejo, Xu Chen, Krishna Jayant, Uma K. Aryal, , Chris Rochet

This study links phosphoproteome modifications to cortical circuit dysfunction in early-stage alpha-synuclein aggregation using multi-omics analysis in rat and mouse models.

bioRxiv · Jan 24, 2025 · PreprintNeuroscience

Neuropathology-based GWAS for Alzheimer's disease reveals novel susceptibility loci and highlights sex-specific pathways

Yin Hua Jin, Apostolia Topaloudi, Sudhanshu Shekhar, Alicia Nicole Scott, Bryce David Colon, Petros Drineas B, Chris Rochet, Peristera Paschou

medRxiv · Dec 17, 2023 · PreprintGenetic & Genomic Medicine

Protective effects of polyphenol-rich extracts against neurotoxicity elicited by paraquat or rotenone in cellular models of Parkinson's disease

Mitali Arun Tambe, Aurélie de Rus Jacquet, Katherine E. Strathearn, Jennifer A. Hensel, Bryce David Colon, Aswathy Chandran, Gad G. Yousef, Mary H. Grace, Mário G. Ferruzzi, Qingli Wu, James Edward Simon, Mary Ann Lila, Jean‐Christophe Rochet

The paper investigates the neuroprotective effects of polyphenol-rich extracts against paraquat and rotenone-induced neurotoxicity in Parkinson's disease models, identifying mechanisms involving antioxidant pathways and mitochondrial function.

Antioxidants · Jul 20, 2023Peer-reviewedNeuroscience