Author

C. A. Ladaika

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

H. M. O'Hagan· 3 shared A. H. Ghobashi· 2 shared S. A. Miller· 2 shared G. E. Zentner· 1 shared R. A. Policastro· 1 shared R. Lanzloth· 1 shared S. Sriramkumar· 1 shared T. D. Huntington· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCancer Biology

H. M. O'Hagan

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3 papers

Recent·Most cited

Single-cell multi-omics reveals insights into differentiation of rare cell types in mucinous colorectal cancer

C. A. Ladaika, A. H. Ghobashi, W. C. Boulton, S. A. Miller, H. M. O'Hagan

The paper uses single-cell multi-omics to study EEC differentiation in mucinous colorectal cancer, identifies STAT3 as a regulator, and discovers a rare cancer cell type with neuron-like features.

bioRxiv · Feb 1, 2024 · PreprintCancer Biology

Single-cell profiling reveals the impact of genetic alterations on the differentiation of inflammation-induced colon tumors

A. H. Ghobashi, R. Lanzloth, C. A. Ladaika, H. M. O'Hagan

This study uses single-cell RNA-sequencing to show how genetic mutations in a mouse model alter colon tumor differentiation in inflammation-induced colorectal cancer.

bioRxiv · Nov 30, 2023Cancer Biology

LSD1 promotes secretory cell specification to drive BRAF mutant colorectal cancer

S. A. Miller, R. A. Policastro, S. Sriramkumar, T. Lai, T. D. Huntington, C. A. Ladaika, G. E. Zentner, H. M. O'Hagan

The paper identifies LSD1 as a regulator of secretory cell specification in BRAF-mutant colorectal cancer, showing its role in tumor growth and metastasis.

bioRxiv · Sep 25, 2020 · PreprintCancer Biology