Author

A. H. Ghobashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

H. M. O'Hagan· 2 shared K. P. Nephew· 2 shared S. Sriramkumar· 2 shared H. M. OHagan· 1 shared J. J. Turchi· 1 shared J. W. Kimani· 1 shared K. S. Pawelczak· 1 shared P. S. VanderVere-Carozza· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

H. M. O'Hagan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivJan 31, 2023

Activation of AKT induces EZH2-mediated beta-catenin trimethylation in colorectal cancer

A. H. Ghobashi, T. T. Vuong, J. W. Kimani, H. M. O'Hagan

This study shows that AKT activation in colorectal cancer leads to EZH2-mediated beta-catenin methylation, enhancing gene expression and promoting tumor progression.

DOI 10.1016/j.isci.2023.107630

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyJournal of Translational MedicinePeer-reviewedMay 31, 2022

Platinum-Induced Mitochondrial OXPHOS Contributes to Cancer Stem Cell Enrichment in Ovarian Cancer

S. Sriramkumar, R. Sood, T. D. Huntington…·H. M. OHagan

This study shows platinum treatment increases mitochondrial activity and OXPHOS in ovarian cancer cells, leading to enrichment of cancer stem cells, which can be blocked by OXPHOS inhibitors.

DOI 10.1186/s12967-022-03447-y

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyMolecular Cancer ResearchPeer-reviewedNov 1, 2020

Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A is Mediated by Replication Protein A in Ovarian Cancer

S. Sriramkumar, T. D. Matthews, A. H. Ghobashi…·H. M. O'Hagan

This study identifies RING1A-mediated ubiquitination of phosphorylated H2AX at platinum DNA damage sites in ovarian cancer, revealing its role in DNA repair and platinum resistance.

DOI 10.1158/1541-7786.mcr-20-0396

humanDNA methylation

𝕏 PostBluesky