Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes
A. Unapanta, F. Shavarebi, J. Porath, C. Balen, A. Nguyen, J. Tseng, Y. Shen, M. Liu, P. Lis, S. Di Pietro, A. Hiniker
This study identifies Rab38 as a physiological regulator of LRRK2 function in melanocytes, showing it enhances LRRK2 membrane recruitment and substrate phosphorylation.
bioRxiv · Jun 20, 2022Cell Biology