Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response.
A. Lima, A. Leyva, B. Rivera, M. M. Portela, M. Gil, A. Cascioferro, M. N. Lisa, A. M. Wehenkel, M. Bellinzoni, P. Carvalho, C. Batthyany, M. N. Alvarez, R. Brosch, P. M. Alzari, R. Duran
This study uses proteomics to show that PknG knockout in M. tuberculosis alters the proteome, affecting cell envelope biosynthesis and hypoxia response.
bioRxiv · Mar 16, 2021Biochemistry