MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis
D. Kantar, E. Bousquet Mur, M. Mancini, V. Slaninova, Y. Ben Salah, L. Costa, E. Forest, P. Lassus, C. Geminard, F. Boissiere-Michot, B. Orsetti, C. Theillet, J. Colinge, C. Benistant, A. Maraver, , A. Djiane
The paper shows that MAGI1 loss in luminal breast cancer promotes tumorigenesis by activating the AMOTL2/p38 stress pathway, which is inhibited by MAGI1.
bioRxiv · Jun 13, 2020Cancer Biology