Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
A. M. Rahman, A. S. T. Engelsen, S. Sarowar, C. Bindesboll, E. Birkeland, M. L. Lotsberg, S. Knappskog, A. Simonsen, M. Chekenya
This study shows bortezomib blocks temozolomide-induced autophagy in GBM cells via an ATG5-dependent pathway, enhancing TMZ efficacy.
bioRxiv · Dec 20, 2020Cancer Biology