Author

C. Bourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Charles· 2 shared D. A. Scheinberg· 2 shared B. Corless· 1 shared D. Tan· 1 shared J. Romero-Pichardo· 1 shared K. Kurtz· 1 shared K. Vogt· 1 shared M. Bah· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

A. Charles

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Host-cell Interactions of Engineered T cell Micropharmacies

C. Bourne, P. Wallisch, M. Dacek, T. Gardner, S. Pierre, K. Vogt, B. Corless, M. Bah, J. Romero-Pichardo, A. Charles, K. Kurtz, D. Tan, D. A. Scheinberg

This study demonstrates that SEAKER cells, engineered T cells with prodrug-activating functions, effectively target solid tumors in immunocompetent hosts despite immune responses.

bioRxiv · Apr 5, 2023 · PreprintImmunology

Low-Dose CDK4/6 Inhibitors Induce Presentation of Pathway Specific MHC ligands as Targets for Cancer Immunotherapy

A. Charles, C. Bourne, S. S. Mun, T. Dao, Z. Aretz, T. Korontsvit, M. Klatt, D. A. Scheinberg

This study shows low-dose CDK4/6 inhibitors increase HLA ligand presentation from cell cycle proteins, creating potential targets for immunotherapy in breast cancer.

bioRxiv · Jun 18, 2020Cancer Biology