Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia
M. A. Swanson, H. Jiang, N. Busquet, J. Carlsen, C. Brindley, T. A. Benke, R. A. Van Hove, M. W. Friederich, K. N. MacLean, M. A. Mesches, J. L. Van Hove
This paper describes a new mouse model of nonketotic hyperglycinemia with postnatal abnormalities in glycine levels, neural tube defects, body weight, electroencephalographic recordings, and activity, useful for evaluating new therapies.
bioRxiv · Mar 26, 2024Animal Behavior & Cognition