Division and adaptation to host nutritional environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelles remodelling
N. J. Katris, S. Amiar, L. Berry, S. Dass, M. J. Shears, C. Brunet, B. Touquet, M.-A. Hakimi, G. I. McFadden, Y. Yamaryo-Botte, C. Y. Botte
This study shows that apicomplexan parasites adapt to host nutritional changes by shifting lipid acquisition between de novo synthesis and host scavenging, involving apicoplast lipid metabolism and host organelle remodeling.
bioRxiv · Mar 22, 2019Microbiology