Exposure of gut bacterial isolates to the anthelminthic drugs, ivermectin and moxidectin, leads to antibiotic-like phenotypes of growth inhibition and adaptation.
J. Dommann, J. Keiser, J. Garneau, A. Gandelin, C. Casanova, P. M. Keller, S. Sayasone, P. Vonaesch, P. Schneeberger
This study shows that ivermectin and moxidectin inhibit gut bacterial growth and induce antibiotic-like resistance, raising concerns about cross-resistance to other antibiotics.
bioRxiv · Jan 17, 2024Microbiology