Author

C. Chintha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Carlesso· 1 shared A. M. Gorman· 1 shared A. Samali· 1 shared L. A. Eriksson· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

A. Carlesso

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1 paper

Recent·Most cited

Structural distortions induced by Kinase Inhibiting RNase Attenuator (KIRA) compounds prevent the formation of face-to-face dimers of Inositol Requiring Enzyme 1α

A. Carlesso, C. Chintha, A. M. Gorman, A. Samali, L. A. Eriksson

This paper investigates how KIRA compounds disrupt IRE1α dimer formation, inhibiting RNase activity and UPR activation through structural and computational analysis.

bioRxiv · Aug 22, 2019Biochemistry