Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells.
A. Goodspeed, A. Bodlak, A. B. Duffy, S. Nelson-Taylor, N. Oike, R. Shirai, D. Walker, T. E. Porfilio, A. Treece, J. O. Black, N. Donaldson, C. Cost, T. Garrington, B. Greffe, S. Luna-Fineman, , M. Hayashi
This study uses single-cell RNA-sequencing to analyze transcriptional heterogeneity in Ewing sarcoma and identifies TSPAN8 as a novel therapeutic target.
bioRxiv · Jan 18, 2024 · PreprintCancer Biology