Author

C. D. Eberhard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. C. Orsburn· 4 shared N. N. Bumpus· 2 shared A. K. Daitch· 1 shared A. M. Gausepohl· 1 shared C. J. White· 1 shared D. F. Kreitler· 1 shared D. W. Williams· 1 shared E. D. Goley· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersPharmacology & Toxicology

B. C. Orsburn

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Tenofovir Activation is Diminished in the Brain and Liver of Creatine Kinase Brain-Type Knockout Mice

C. D. Eberhard, E. P. Mosher, N. N. Bumpus, B. C. Orsburn

This paper shows that CKB knockout mice have reduced tenofovir activation in brain and liver, with specific mutations impairing CKB's ability to generate the active metabolite TFV-DP.

bioRxiv · Sep 25, 2023Pharmacology & Toxicology

Acetic acid is a superior ion pairing modifier for sub-nanogram and single cell proteomics

C. D. Eberhard, B. C. Orsburn

This paper shows that acetic acid improves peptide signal and proteome coverage in sub-nanogram and single cell proteomics compared to formic acid.

bioRxiv · Aug 1, 2023 · PreprintBiochemistry

Spatial Heterogeneity of Brain Lipids in SIV-infected Macaques Treated with Antiretroviral Therapy

C. J. White, A. M. Gausepohl, H. N. Wilkins, C. D. Eberhard, B. C. Orsburn, D. W. Williams

This study examines spatial lipid changes in SIV-infected macaques on ART, finding region-specific lipid alterations that suggest ongoing bioenergetic disruptions in the brain.

bioRxiv · Sep 26, 2022Pathology

EstG is a novel esterase required for cell envelope integrity

A. K. Daitch, B. C. Orsburn, Z. Chen, L. Alvarez, C. D. Eberhard, K. Sundararajan, R. Zeinert, D. F. Kreitler, J. Jakoncic, P. Chien, F. Cava, S. B. Gabelli, N. N. Bumpus, E. D. Goley

This study identifies EstG, a novel esterase in Caulobacter crescentus that protects against cellular stress by acting on cyclic osmoregulated periplasmic glucans rather than the cell wall.

bioRxiv · Apr 12, 2022Microbiology