Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape
B. Hunter, M. P. M. H. Benoit, A. B. Asenjo, C. Doubleday, D. Trofimova, H. Sosa, J. S. Allingham
This study defines the mechanism of kinesin-8 dual activity by showing how loop-2 regulates motor domain conformation based on tubulin protofilament shape.
bioRxiv · Feb 28, 2022Biochemistry