GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data
S. A. Ajaib, D. Lodha, S. Pollock, G. Hemmings, M. Finetti, A. Gusnanto, A. Chakrabarty, A. Ismail, E. Wilson, F. S. Varn, B. Hunter, A. Filby, A. A. Brockman, D. McDonald, R. Verhaak, , L. F. Stead
This paper develops GBMdeconvoluteR, a tool to accurately infer neoplastic and immune cell proportions in bulk glioblastoma RNAseq data, validated against imaging mass cytometry.
Neuro-Oncology · Jul 6, 2023Peer-reviewedCancer Biology