Immune cell regulation in stem cell niche contacting glioblastomas.
T. Bartkowiak, S. M. Lima, M. J. Hayes, A. M. Mistry, J. Sinnaeve, N. Leelatian, C. E. Roe, B. C. Mobley, K. D. Weaver, R. C. Thompson, L. B. Chambless, R. A. Ihrie, J. M. Irish
This study shows that glioblastomas contacting the lateral ventricle have distinct immune features, including elevated T cell checkpoint receptors and suppressive myeloid cells, suggesting new therapeutic targets.
bioRxiv · Feb 16, 2022 · PreprintImmunology