Author

S. Schaefer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

A. A. Widjaja· 1 shared A. A. Wurm· 1 shared A. Julia· 1 shared A. K. Cain· 1 shared A. Loizides· 1 shared A. Paulo· 1 shared A. Pedrini· 1 shared A. R. Shiakolas· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 5 mutual co-author links

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1 shared paperImmunology

A. A. Widjaja

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A regulatory gene network that couples floral transition to shoot apical meristem morphology in Arabidopsis

E. Bertran Garcia de Olalla, G. Rodriguez-Maroto, M. Cerise, A. Vayssieres, E. Severing, Y. Lopez-Sampere, K. Wang, S. Schaefer, P. Formosa-Jordan, G. Coupland

The paper shows reciprocal repression between AP2 and SOC1 transcription factors couples floral transition to changes in shoot apical meristem morphology in Arabidopsis.

bioRxiv · May 10, 2024Plant Biology

The histone modifier KAT2A presents a selective target in a subset of well-differentiated microsatellite-stable colorectal cancers

V. Kufrin, A. Seiler, S. Brilloff, H. Rothfuss, S. Schuster, S. Schaefer, E. Rahimian, J. Baumgarten, C. R. Ball, M. Bornhaeuser, H. Glimm, M. Bill, A. A. Wurm

This study identifies KAT2A as a therapeutic target in a subset of well-differentiated, microsatellite-stable colorectal cancers by showing its dependency and functional consequences.

bioRxiv · Nov 15, 2023Cancer Biology

scDrugPrio: A framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases

S. Schaefer, M. Smelik, O. Sysoev, Y. Zhao, D. Eklund, S. Lilja, M. Gustafsson, H. Heyn, A. Julia, I. A. Kovacs, J. Loscalzo, S. Marsal, H. Zhang, X. Li, D. Gawel, , M. Benson

scDrugPrio uses single-cell RNA sequencing to prioritize drugs for immune-mediated inflammatory diseases, showing personalized drug response variations across patients.

bioRxiv · Nov 8, 2023Immunology

A synthetic peptide mimic kills Candida albicans and synergistically prevents infection

S. Schaefer, R. Vij, J. L. Sprague, S. Austermeier, H. Dinh, P. R. Judzewitsch, E. Seemann, B. Qualmann, A. K. Cain, N. Corrigan, M. S. Gresnigt, C. Boyer, M. D. Lenardon, S. Brunke

This study identifies synthetic peptide mimics that kill Candida albicans and synergize with caspofungin to prevent infection, showing efficacy in vitro and in vivo without resistance development.

bioRxiv · Sep 25, 2023Microbiology

Interleukin-11 plays a key role in human and mouse alcohol-related liver disease

M. Effenberger, F. Grabherr, B. Schaefer, C. Grander, L. Mayr, J. Schwaerzler, B. Enrich, P. Moser, J. Fink, A. Pedrini, N. Jaschke, M. Freund, A. Loizides, R. Bale, D. Putzer, , H. Tilg

This study shows IL-11 is elevated in severe liver disease and blocking it reduces inflammation in alcohol-related liver disease in humans and mice.

bioRxiv · Aug 24, 2021 · PreprintImmunology

Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine

K. J. Kramer, E. M. Wilfong, K. Voss, S. Barone, A. R. Shiakolas, N. Raju, C. E. Roe, N. Suryadevara, L. M. Walker, S. C. Wall, A. Paulo, S. Schaefer, D. Dahunsi, C. S. Westlake, J. E. Crowe, , J. M. Irish

bioRxiv · Jul 28, 2021Immunology