Author

C. E. Strohlein

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Immunology· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. H. Sawalha· 1 shared M. G. Dozmorov· 1 shared S. Bastacky· 1 shared X. Zheng· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

A. H. Sawalha

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1 paper

Recent·Most cited

Ezh2 knockout in B cells impairs plasmablast differentiation and ameliorates lupus-like disease in MRL/lpr mice

X. Zheng, M. G. Dozmorov, C. E. Strohlein, S. Bastacky, A. H. Sawalha

This study shows that deleting EZH2 in B cells reduces autoantibody production and improves lupus-like disease in MRL/lpr mice by impairing plasmablast differentiation.

bioRxiv · Jul 21, 2022 · PreprintImmunology