Circadian clock genes Bmal1 and Per2 in the nucleus accumbens are negative regulators of alcohol-drinking behavior in mice.
J. Herrera, Margo Button, P. Doherty-Haigh, C. Goldfarb, Nour Quteishat, Shimon Amir, Konrad Schoettner
This study shows that Bmal1 and Per2 in the nucleus accumbens reduce alcohol consumption in male mice, but not in females, with Bmal1's effect being specific to the nucleus accumbens in females.
bioRxiv · Feb 24, 2023 · PreprintNeuroscience