A role for the putative error-prone polymerase REV1 in DNA damage and antifungal drug resistance in Candida albicans
M. R. Agyare-Tabbi, D. Uthayakumar, D. Francis, L. Maroc, C. Grant, P. McQueen, G. Westmacott, H. Shaker, I. Skulska, I. Gagnon-Arsenault, J. Boisvert, C. Landry, R. S. Shapiro
This study investigates the role of REV1, an error-prone polymerase, in DNA damage and antifungal drug resistance in Candida albicans, finding that its deletion increases mutation rates and resistance.
bioRxiv · Jun 24, 2024 · PreprintMicrobiology