C. Landry

Cryptic genetic variation shapes the fate of gene duplicates in a protein interaction network

The paper shows that mutations in protein binding domains, combined with regulatory divergence, determine the fate of gene duplicates in a protein interaction network.

Hybrid adaptation is hampered by Haldane's sieve

The paper shows that hybrid yeast adaptation is slowed by Haldane's sieve due to slower loss of heterozygosity and incomplete dominance of adaptive mutations.

The substrate quality of CK2 target sites has a determinant role on their function and evolution

The paper investigates how substrate quality affects the function and evolution of CK2 phosphosites, showing that optimal sites are more conserved and functionally important than minimal ones.

Evolutionary trajectories are contingent on mitonuclear interactions

This study shows that mitonuclear interactions shape evolutionary divergence in yeast populations with identical nuclear genotypes under different environmental pressures.

Breaking dormancy in spores of budding yeast transforms its cytoplasm and the solubility of its proteome

This study shows that spore germination in budding yeast involves changes in cytoplasmic biophysical properties and proteome solubility, regulated by Hsp42.

The rate of whole-genome duplication can be accelerated by hybridization

This study shows hybridization can trigger whole-genome duplication (WGD) in yeast, increasing fertility and genetic variability, and that some genotypes are more prone to WGD.

The BUBR1 pseudokinase domain promotes efficient kinetochore PP2A-B56 recruitment to regulate spindle checkpoint silencing and chromosome alignment

This study shows the BUBR1 pseudokinase domain enhances PP2A-B56 recruitment to kinetochores, ensuring proper checkpoint silencing and chromosome alignment by modulating phosphorylation.

A systems biology approach to explore the impact of maple tree dormancy release on sap variation and maple syrup quality

The paper investigates sap composition changes during maple tree dormancy release and links them to syrup quality and the buddy defect using amino acid analysis and yeast competition assays.