R. S. Shapiro

This study tests antimicrobial susceptibility of three Malassezia species to four drugs, finding isavuconazole and artemisinin effective and itraconazole most potent.

This paper develops a CRISPR activation system for genetic overexpression in Candida albicans and demonstrates its ability to drive high-level gene expression and identify novel phenotypes.

This study identifies Efg1- and Als1-dependent mechanisms by which Candida albicans forms biofilms and causes infection in the catheterized bladder environment.

This study identifies Tra1 as a key regulator of drug resistance and pathogenesis in Candida albicans by analyzing gene expression and mutant phenotypes.

The paper systematically characterizes adhesins in Candida albicans and identifies genetic interactions affecting virulence using a CRISPR-based mutant library and C. elegans model.

The paper shows that metabolism-induced oxidative stress and DNA damage cause genome instability specifically in polyploid cells of C. albicans, not diploid cells.