RIG-I-induced innate antiviral immunity protects mice from lethal SARS-CoV-2 infection
S. Marx, B. M. Kuemmerer, C. Gruetzner, H. Kato, M. Schlee, E. Bartok, M. Renn, G. Hartmann
This study shows that activating the RIG-I receptor with synthetic RNA oligonucleotides before SARS-CoV-2 infection improves mouse survival and reduces viral load.
bioRxiv · Aug 6, 2021Immunology