Interactions between Nodal and Wnt signalling Drive Robust Symmetry Breaking and Axial Organisation in Gastruloids (Embryonic Organoids)
D.A. Turner, C.R. Glodowski, L. Alonso-Crisostomo, P. Baillie-Johnson, P.C. Hayward, J. Collignon, C. Gustavsen, P. Serup, C. Schröter, A. Martinez Arias
This study uses Gastruloids to show that Nodal and Wnt signaling interactions drive symmetry breaking and axial organization in early development.
bioRxiv · May 13, 2016 · PreprintDevelopmental Biology