Pharmacology & ToxicologyReproductive ToxicologyPeer-reviewed
In vitro teratogenicity testing using a 3D, embryo-like gastruloid system
V. Mantziou, P. Baillie-Benson, M. Jaklin…·N. Moris
This study uses a 3D gastruloid model to assess teratogenicity of seven reference compounds in mouse and human systems, showing morphological and gene expression changes indicative of developmental defects.