SARS-CoV-2 envelope-protein corruption of homeostatic signaling mechanisms in mammalian cells
T. Schulze, A. Hartel, S. Hoeler, C. Hemming, R. Lehn, D. Tandl, T. Greiner, A. Bertl, K. Shepard, A. Moroni, G. Thiel, O. Rauh
This study shows that SARS-CoV-2 envelope protein disrupts cellular homeostasis by forming ion channels, leading to altered Ca2+ and pH levels and membrane depolarization.
bioRxiv · Jun 16, 2021 · PreprintPathology