GITR and TIGIT immunotherapy provokes divergent multi-cellular responses in the tumor microenvironment of gastrointestinal cancers
A. Sathe, C. Ayala, X. Bai, S. M. Grimes, B. Lee, C. Kin, A. Shelton, G. Poultsides, H. Ji
The paper examines GITR and TIGIT immunotherapies in gastrointestinal cancers using ex vivo cultures and single-cell sequencing to identify their cellular mechanisms in the tumor microenvironment.
bioRxiv · Mar 13, 2023 · PreprintCancer Biology