Author

C. Kline

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:DNA methylation· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Z. Ambrose· 2 shared A. D. Kashuba· 1 shared A. F. Feder· 1 shared A. K. Hughson· 1 shared A. N. Engelman· 1 shared B. F. Keele· 1 shared D. A. Petrov· 1 shared G. A. Sowd· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Z. Ambrose

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration

Z. Ingram, C. Kline, A. K. Hughson, P. K. Singh, H. L. Fischer, G. A. Sowd, S. C. Watkins, M. Kane, A. N. Engelman, Z. Ambrose

This study shows that sequential binding of CypA and CPSF6 to HIV-1 capsid is necessary for nuclear entry and integration, and that lenacapavir targets this process.

bioRxiv · Apr 8, 2024Microbiology

High resolution spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host

A. F. Feder, C. Kline, P. Polacino, M. Cottrell, A. D. Kashuba, B. F. Keele, S.-L. Hu, D. A. Petrov, P. Pennings, Z. Ambrose

This study tracks SHIV evolution in macaques to show drug resistance spreads rapidly across compartments but does not equilibrate, with the gut showing faster turnover and less wild-type virus retention.

bioRxiv · Jan 4, 2017Evolutionary Biology