Author

M. Cottrell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

A. D. Kashuba· 3 shared B. F. Keele· 2 shared A. F. Feder· 1 shared A. Schauer· 1 shared B. Policicchio· 1 shared C. Apetrei· 1 shared C. Kline· 1 shared C. Sykes· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersPharmacology & Toxicology

A. D. Kashuba

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Validation of an LC-MS/MS Assay for the Simultaneous Determination of Bictegravir, Doravirine, and Raltegravir in Human Plasma

A. Schauer, C. Sykes, M. Cottrell, A. D. Kashuba

The paper validates an LC-MS/MS method to simultaneously measure Bictegravir, Doravirine, and Raltegravir in human plasma across a wide range.

bioRxiv · May 21, 2020Pharmacology & Toxicology

Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques

E. Brocca-Cofano, C. Xu, K. Wetzel, M. Cottrell, B. Policicchio, K. Raehtz, D. Ma, T. Dunsmore, G. Haret-Richter, K. Musaitif, B. F. Keele, A. D. Kashuba, R. Collman, I. Pandrea, C. Apetrei

This study evaluates the effectiveness of maraviroc in preventing oral SIV transmission to infant macaques, finding only marginal impact despite CCR5 blockade.

bioRxiv · Apr 11, 2018Immunology

High resolution spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host

A. F. Feder, C. Kline, P. Polacino, M. Cottrell, A. D. Kashuba, B. F. Keele, S.-L. Hu, D. A. Petrov, P. Pennings, Z. Ambrose

This study tracks SHIV evolution in macaques to show drug resistance spreads rapidly across compartments but does not equilibrate, with the gut showing faster turnover and less wild-type virus retention.

bioRxiv · Jan 4, 2017Evolutionary Biology