Author

C. L. Kufner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:statistical model· 1

Frequent Co-Authors

C. B. Mast· 2 shared D. B. Bucher· 2 shared D. Braun· 2 shared H. Blum· 2 shared J. Philippou-Massier· 2 shared M. Fischaleck· 2 shared W. Zinth· 2 shared D. D. Sasselov· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

C. B. Mast

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3 papers

Recent·Most cited

The Unexpected Functional Diversity of Photoexcited NAD

C. L. Kufner, M. J. Janicki, G. G. Lozano, D. D. Sasselov

This paper investigates the ultrafast photodynamics of NAD+ and NADH using spectroscopy and quantum-chemical calculations, revealing a long-lived charge-separated state in NADH and new functional roles.

bioRxiv · Oct 19, 2023 · PreprintBiophysics

Selection of the Early Genetic Code by Ultraviolet Light

C. L. Kufner, S. B. Krebs, M. Fischaleck, J. Philippou-Massier, H. Blum, D. B. Bucher, D. Braun, W. Zinth, C. B. Mast

This study quantifies UV stability of DNA sequences and simulates photodamage to proto-genomes, showing UV compatibility of early life and ranking codon evolutionary models by UV resistance.

bioRxiv · Oct 13, 2022 · PreprintBiophysics

Sequence Dependent UV Damage of Complete Pools of Oligonucleotides

C. L. Kufner, S. Krebs, M. Fischaleck, J. Philippou-Massier, H. Blum, D. B. Bucher, D. Braun, W. Zinth, C. B. Mast

The paper quantifies UV damage susceptibility of all 4096 hexamer DNA sequences using high-throughput sequencing, revealing sequence context effects on lesion formation.

bioRxiv · Aug 1, 2022Biophysics