The ATP-exporting channel Pannexin-1 promotes CD8+ T cell effector and memory responses
T. Vardam-Kaur, A. Banuelos, M. Gabaldon-Parish, B. G. Macedo, C. L. Salgado, K. M. Wanhainen, M. H. Zhou, S. van Dijk, I. Santiago-Carvalho, A. S. Beniwal, C. L. Leff, C. Peng, N. L. Tran, S. C. Jameson, H. Borges da Silva
This study shows that Pannexin-1 promotes CD8+ T cell effector and memory responses through distinct mechanisms involving eATP export and purinergic receptor activation.
bioRxiv · Apr 19, 2023Immunology