Author

C. Lungu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

R.-J. Palstra· 2 shared S. Rao· 2 shared T. Mahmoudi· 2 shared A. Braun· 1 shared A. Gorska· 1 shared A. Ngubane· 1 shared A. Verbon· 1 shared B. Noll· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

R.-J. Palstra

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Author profile →

3 papers

Recent·Most cited

SQuHIVLa: A novel assay for Specific Quantification of inducible HIV-1 reservoir by LAMP

T. Hossain, C. Lungu, S. de Schrijver, M. Kuali, S. Rao, A. Ngubane, T. W. Kan, R.-J. Palstra, P. Madlala, T. Ndung'u, T. Mahmoudi

SQuHIVLa quantifies inducible HIV-1 reservoirs in CD4+ T cells using a sensitive and specific RT-LAMP assay, showing high throughput and scalability.

bioRxiv · Jul 14, 2023 · PreprintMicrobiology

The GEF-GAP pair Solo and DLC3 balances Rho activity during endocytic transport

C. Lungu, F. Meyer, M. Hörning, J. Steudle, A. Braun, B. Noll, D. Benz, F. Frankle, S. Schmid, S. A. Eisler, M. A. Olayioye

This study identifies Solo and DLC3 as a RhoGAP-RhoGEF pair that regulates RhoB activity and levels during endocytic transport through combined RNAi screening and biochemical assays.

bioRxiv · Mar 1, 2022 · PreprintCell Biology

Induction of selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir

S. Rao, C. Lungu, R. Crespo, T. H. Steijaert, A. Gorska, R.-J. Palstra, H. A. B. Prins, W. van Ijcken, C. Rokx, Y. M. Mueller, J. J. A. Van Kampen, A. Verbon, P. D. Katsikis, C. A. B. Boucher, R. A. Gruters, T. Mahmoudi

This study shows DDX3 inhibitors induce selective apoptosis in HIV-1-infected cells, reducing the inducible latent HIV-1 reservoir.

bioRxiv · Aug 26, 2020Microbiology