A. Braun

SARS-CoV-2 modulates NK cell responses via induction of HLA-E and triggers expansion of adaptive NK cells during acute infection

This study shows SARS-CoV-2 increases HLA-E expression via spike protein processing, modulating NK cell function by affecting canonical and adaptive NK cells differently during acute infection.

A Simple and Rapid Protocol for the Isolation of Murine Bone Marrow Suitable for the Differentiation of Dendritic Cells

This paper introduces a centrifugation-based method for isolating murine bone marrow to differentiate dendritic cells, which increases cell numbers and yields more type 1 conventional dendritic cells.

REM-like Oscillatory Theta Activity Predicts a Reduction in the Recuperative Value of Natural Human Sleep

The paper examines whether REM sleep incurs sleep debt by developing a novel measure of REM-like theta activity and finding it correlates with increased sleep debt.

Early induction of severe cytokine release syndrome by rapidly generated CAR T cells in a preclinical mouse model

This study shows that rapidly generated CAR T cells induce severe cytokine release syndrome in a mouse model within 24 hours.

The GEF-GAP pair Solo and DLC3 balances Rho activity during endocytic transport

This study identifies Solo and DLC3 as a RhoGAP-RhoGEF pair that regulates RhoB activity and levels during endocytic transport through combined RNAi screening and biochemical assays.

The self-peptide repertoire plays a critical role in transplant tolerance induction

This study identifies immunogenic MHC I peptides involved in transplant tolerance by combining genetic engineering, immunopeptidomics, and T cell analysis.

Marmoset monkeys (Callithrix jacchus) develop eosinophilic airway inflammation after house dust mite exposure

This study shows marmoset monkeys develop eosinophilic airway inflammation after house dust mite exposure, useful for testing new human-specific biologicals.