Author

C. M. Backlund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. J. Irvine· 2 shared M. E. Birnbaum· 2 shared N. K. Singh· 2 shared B. D. Huisman· 1 shared B. E. Grace· 1 shared B. H. Kang· 1 shared B. Kim· 1 shared C. G. Rappazzo· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

D. J. Irvine

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Author profile →

2 papers

Recent·Most cited

Decoupled neoantigen cross-presentation in tumors with high intratumor heterogeneity reduces dendritic cell activation to limit anti-tumor immunity

K. B. Nguyen, C. J. Copeland, C. M. Backlund, N. G. Klop-Packel, T. Remba, B. Kim, N. K. Singh, M. E. Birnbaum, D. J. Irvine, S. Spranger

This study shows that clonal neoantigen expression enhances dendritic cell activation and anti-tumor immunity, while subclonal expression reduces it in tumors with high intratumor heterogeneity.

bioRxiv · Dec 16, 2022Immunology

Identification of highly cross-reactive mimotopes for a public T cell response in murine melanoma

B. E. Grace, C. M. Backlund, D. M. Morgan, B. H. Kang, N. K. Singh, B. D. Huisman, C. G. Rappazzo, K. D. Moynihan, L. Maiorino, C. S. Dobson, T. Kyung, K. S. Gordon, P. V. Holec, O. C. T. Mbah, D. Garafola, , M. E. Birnbaum

The paper identifies a dominant tumor-associated antigen in murine melanoma and shows that engineered mimotopes can induce cross-reactive T cell responses.

bioRxiv · Feb 28, 2022Immunology