Author

C. M. Driggers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

S.-L. Shyng· 2 shared A. ElSheikh· 1 shared B. L. Patton· 1 shared B. Mostofian· 1 shared D. M. Zuckerman· 1 shared J. D. Russo· 1 shared M. W. Sung· 1 shared P. Zhu· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

S.-L. Shyng

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2 papers

Recent·Most cited

Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface

C. M. Driggers, Y.-Y. Kuo, P. Zhu, A. ElSheikh, S.-L. Shyng

This study reports the cryoEM structure of an open KATP channel with PIP2 bound, revealing two PIP2 binding sites and their role in channel regulation and neonatal diabetes.

bioRxiv · Aug 1, 2023 · PreprintBiochemistry

Ligand-mediated structural dynamics of a mammalian pancreatic KATP channel

M. W. Sung, C. M. Driggers, B. Mostofian, J. D. Russo, B. L. Patton, D. M. Zuckerman, S.-L. Shyng

The paper investigates how ligands affect the structural dynamics of pancreatic KATP channels using cryo-EM and molecular dynamics simulations.

bioRxiv · Mar 2, 2022Biochemistry