Author

C. Novais

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:whole-genome sequencing· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:E. coli· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:variant calling· 2

Frequent Co-Authors

A. R. Freitas· 4 shared L. Peixe· 4 shared P. Antunes· 4 shared T. M. Coque· 4 shared A. Novais· 2 shared A. P. Pereira· 2 shared A. Rebelo· 2 shared J. Corander· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersMicrobiology

A. R. Freitas

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Author profile →

6 papers

Recent·Most cited

Decoding Klebsiella pneumoniae in Poultry Chain: Unveiling Genetic Landscape, Antibiotic Resistance, and Biocide Tolerance in Non-Clinical Reservoirs

J. Mourao, M. Magalhaes, M. Ribeiro-Almeida, A. Rebelo, C. Novais, L. V. Peixe, A. Novais, P. Antunes

This study characterizes K. pneumoniae in poultry production, revealing its genetic diversity, antibiotic resistance, and biocide tolerance across the farm-to-fork chain.

bioRxiv · Jan 23, 2024 · PreprintMicrobiology

From farm to fork: persistence of clinically-relevant multidrug-resistant and copper-tolerant Klebsiella pneumoniae long after colistin withdrawal in poultry production.

J. Mourao, M. Ribeiro-Almeida, C. Novais, M. Magalhaes, A. Rebelo, S. Ribeiro, L. V. Peixe, A. Novais, P. Antunes

This study shows that colistin-resistant and copper-tolerant Klebsiella pneumoniae persist in poultry production despite long-term colistin withdrawal and copper supplementation.

bioRxiv · Apr 3, 2023Microbiology

The population-level impact of Enterococcus faecalis genetics on intestinal colonisation and extraintestinal infection

C. Chaguza, A. K. Pöntinen, J. Top, S. Arredondo-Alonso, A. R. Freitas, C. Novais, C. Torres, S. D. Bentley, L. Peixe, T. M. Coque, R. J. L. Willems, J. Corander

This study investigates the genetic factors influencing E. faecalis intestinal colonization and extraintestinal infection using GWAS and heritability analysis across 750 isolates.

bioRxiv · Sep 26, 2022 · PreprintMicrobiology

Evolution of chlorhexidine susceptibility and of the EfrEF operon among Enterococcus faecalis from diverse environments, clones and time spans

A. P. Pereira, P. Antunes, R. J. L. Willems, J. Corander, T. M. Coque, L. Peixe, A. R. Freitas, C. Novais

This study examines CHX susceptibility and ChlR-EfrEF variability in E. faecalis isolates from diverse environments, finding increased tolerance in food chain and recent human isolates.

bioRxiv · Jan 27, 2022Microbiology

Fitness cost of vancomycin-resistant Enterococcus faecium plasmids associated with hospital infection outbreaks

A. P. Tedim, V. F. Lanza, C. M. Rodriguez, A. R. Freitas, C. Novais, L. Peixe, F. Baquero, T. M. COQUE

The paper analyzes the fitness cost and stability of vancomycin-resistant plasmids in Enterococcus faecium and E. faecalis, showing reduced host fitness and plasmid stability under selective pressure.

bioRxiv · Jan 27, 2021Microbiology

Identification of 2CS-CHXT operon signature of chlorhexidine tolerance among Enterococcus faecium

B. Duarte, A. P. Pereira, A. R. Freitas, T. M. Coque, A. M. Hammerum, H. Hasman, P. Antunes, L. Peixe, C. Novais

This study identifies a 2CS-CHXT operon signature associated with chlorhexidine tolerance in Enterococcus faecium and proposes an epidemiological cut-off for detection.

bioRxiv · Jul 17, 2019Microbiology