Author

C. O. Ottmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

L. Brunsveld· 2 shared B. A. Somsen· 1 shared E. Semenova· 1 shared G. Nolte· 1 shared J. Hochmair· 1 shared L. Diez· 1 shared L. J. M. Lemmens· 1 shared L. Ravatt· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

L. Brunsveld

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Author profile →

2 papers

Recent·Most cited

Stoichiometric 14-3-3ζ binding promotes phospho-Tau microtubule dissociation and reduces aggregation and condensation

J. Hochmair, M. C. M. van den Oetelaar, L. Ravatt, L. Diez, L. J. M. Lemmens, R. Ponce Lina, R. Sankar, M. W. Franck, G. Nolte, E. Semenova, S. Mohapatra, C. O. Ottmann, L. Brunsveld, S. Wegmann

This study shows that 14-3-3ζ binding to phosphorylated Tau reduces its association with microtubules and inhibits aggregation and condensation.

bioRxiv · Mar 15, 2024 · PreprintBiochemistry

Early identification of cooperative fragments for protein-protein interaction stabilization

P. J. de Vink, P. J. Cossar, B. A. Somsen, C. O. Ottmann, L. Brunsveld

The paper identifies cooperative fragments that stabilize protein-protein interactions using STD NMR and validates their effects through mutagenesis and crystallography.

bioRxiv · Feb 23, 2022 · PreprintBiochemistry