Author

S. Wegmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. Mohapatra· 2 shared A. A. Hyman· 1 shared A. d. S. Pinheiro· 1 shared A. Hernandez-Vega· 1 shared A. R. Passos· 1 shared B. T. Hyman· 1 shared C. O. Ottmann· 1 shared E. Semenova· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

S. Mohapatra

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stoichiometric 14-3-3ζ binding promotes phospho-Tau microtubule dissociation and reduces aggregation and condensation

J. Hochmair, M. C. M. van den Oetelaar, L. Ravatt, L. Diez, L. J. M. Lemmens, R. Ponce Lina, R. Sankar, M. W. Franck, G. Nolte, E. Semenova, S. Mohapatra, C. O. Ottmann, L. Brunsveld, S. Wegmann

This study shows that 14-3-3ζ binding to phosphorylated Tau reduces its association with microtubules and inhibits aggregation and condensation.

bioRxiv · Mar 15, 2024 · PreprintBiochemistry

Copper drives prion protein phase separation and modulates aggregation

M. J. Do Amaral, A. R. Passos, S. Mohapatra, T. S. L. Da Silva, R. S. Carvalho, M. d. S. Almeida, A. d. S. Pinheiro, S. Wegmann, Y. Cordeiro

This study shows copper promotes prion protein condensation and aggregation through oxidative stress and co-partitioning, suggesting a dual role in copper buffering and toxicity.

Science Advances · Nov 3, 2023Peer-reviewedBiophysics

Local Nucleation Of Microtubule Bundles Through Tubulin Concentration Into A Condensed Tau Phase

A. Hernandez-Vega, M. Braun, L. Scharrel, M. Jahnel, S. Wegmann, B. T. Hyman, S. Alberti, S. Diez, A. A. Hyman

The paper shows that tau forms liquid droplets that concentrate tubulin, enabling local microtubule bundle nucleation without centrosomes.

bioRxiv · Apr 12, 2017Cell Biology