C. Prevost

nP-collabs: Investigating counterion mediated bridges in the multiply phosphorylated tau-R2 repeat

This paper uses molecular dynamics simulations to study how counterion bridges formed by phosphate groups affect the conformational dynamics of phosphorylated tau-R2 repeat.

It takes tau to tango: Investigating the fuzzy interaction between the R2-repeat domain and tubulin C-terminal tails

This study investigates the interaction between tau's R2-repeat domain and tubulin C-terminal tails using molecular dynamics simulations to understand how CTTs affect tau-tubulin binding stability and MAP recruitment.

RecA balances genomic stability and evolution using many successive mismatch tolerant homology tests

The paper models how RecA in E. coli balances genomic stability and evolution by testing homology with increasing stringency, predicting that 50 bp of testing is needed for accurate allelic pairing.

Moving pictures: Reassessing docking experiments with a dynamic view of protein interfaces

The paper reassesses docking models of protein complexes using dynamic simulations, showing that over 50% of models change accuracy categories when evaluated with dynamic interface stability criteria.

The sequences near Chi sites allow the RecBCD pathway to avoid genomic rearrangements

The paper shows that Chi sites at the ends of RecBCD-generated ssDNA tails prevent genomic rearrangements by ensuring proper homology search and strand exchange during bacterial recombinational repair.