Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements
B. Tegtmeyer, G. Vieyres, D. Todt, C. Lauber, C. Ginkel, M. Engelmann, M. Herrmann, C. K. Pfaller, F. W. R. Vondran, R. Broering, E. Vafadarnejad, A.-E. Saliba, C. Puff, W. Baumgärtner, C. Miskey, , R. J. P. Brown
This study identifies temporally structured transcriptional changes in HCV-infected human hepatocytes, revealing both antiviral and pro-viral programs that may contribute to viral persistence.
bioRxiv · Feb 12, 2021Immunology