Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells
M. Zwick, T. Ulas, Y.-L. Cho, C. Ried, L. Grosse, C. Simon, C. Bernhard, D. H. Busch, J. L. Schulze, V. Buchholz, S. Stutte, T. Brocker
This study shows that Ppef2 deficiency in CD8+ dendritic cells leads to increased apoptosis and reduced antigen presentation, impacting T cell responses.
bioRxiv · Jul 29, 2018Immunology