Author

C. Siletti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

T. N. Huynh· 2 shared A. B. Banta· 1 shared A. L. Enright· 1 shared A. R. Gall· 1 shared D. Amador-Noguez· 1 shared D. M. Stevenson· 1 shared J. M. Peters· 1 shared J.-D. Sauer· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

T. N. Huynh

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3 papers

Recent·Most cited

C-di-AMP accumulation disrupts glutathione metabolism and inhibits virulence program expression in Listeria monocytogenes

C. Siletti, M. J. Freeman, Z. Tu, D. M. Stevenson, D. Amador-Noguez, J.-D. Sauer, T. N. Huynh

This study shows that c-di-AMP accumulation in Listeria monocytogenes disrupts glutathione metabolism, leading to reduced virulence gene expression and attenuated pathogenesis.

bioRxiv · Jan 18, 2024 · PreprintMicrobiology

NrnA is a linear dinucleotide phosphodiesterase with limited function in cyclic dinucleotide metabolism in Listeria monocytogenes

A. R. Gall, C. Siletti, T. N. Huynh

This study identifies NrnA as a phosphodiesterase in L. monocytogenes that preferentially degrades linear dinucleotides, with limited impact on cyclic dinucleotide levels and no role in regulating their hydrolytic enzymes.

bioRxiv · Apr 21, 2021Microbiology

A High-efficacy CRISPRi System for Gene Function Discovery in Zymomonas mobilis

J. M. Peters, A. B. Banta, A. L. Enright, C. Siletti

This paper develops a high-efficacy CRISPRi system in Zymomonas mobilis to knock down essential genes, enabling gene function discovery and improving biofuel production strains.

Applied and Environmental Microbiology · Nov 10, 2020Peer-reviewedMicrobiology