Modeling tissue-resident macrophage development from mouse pluripotent stem cells
Ann K Baako, Ragavi Vijayakumar, Daniel Medina-Cano, Zhaoquan Wang, Jesús E. Romero-Pichardo, Kelvin Fadojutimi, C. Stephanie, Yuan Lin, Mohammed Tarek Islam, Sanjana Dixit, Alissa J. Trzeciak, Justin S. A. Perry, Thomas Vierbuchen
This paper develops a protocol to efficiently generate tissue-resident macrophages from mouse pluripotent stem cells, enabling in vitro and in vivo modeling of their development.
bioRxiv · May 1, 2025 · PreprintDevelopmental Biology