Ythdf2 regulates cardiac remodeling through its m6A-mRNA target transcripts
Vivien Kmietczyk, J. Oelschläger, P. Gupta, Eshita Varma, S. Hartl, Jennifer Furkel, Mathias H. Konstandin, Alexander Marx, Zoe Loewenthal, Verena Kamuf‐Schenk, Lonny Jürgensen, C. Stroh, Agnieszka A. Gorska, Abel Martín-Garrido, Joerg Heineke, , Mirko Völkers
This study shows that Ythdf2, an m6A reader protein, regulates cardiac function by controlling gene expression through its target transcripts, leading to cardiac remodeling in heart failure models.
Journal of Molecular and Cellular Cardiology · Jun 12, 2023Peer-reviewedMolecular Biology