Author

C. T. Meyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 3 Assay:proteomics· 3 Organism:E. coli· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. M. Kralj· 2 shared A. Chatterjee· 1 shared A. L. Crooks· 1 shared B. Dodd· 1 shared B. Zhou· 1 shared C. F. Lopez· 1 shared C. S. Detweiler· 1 shared C.-C. Su· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersMicrobiology

J. M. Kralj

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Author profile →

4 papers

Recent·Most cited

Bacterial Efflux Pump Modulators Prevent Bacterial Growth in Macrophages and Under Broth Conditions that Mimic the Host Environment

S. C. Allgood, C.-C. Su, A. L. Crooks, C. T. Meyer, B. Zhou, M. D. Betterton, M. R. Barbachyn, E. W. Yu, C. S. Detweiler

This paper identifies and improves efflux pump modulators (EPMs) that inhibit bacterial growth in macrophages and enhance antibiotic potency under host-like conditions.

bioRxiv · Sep 20, 2023Microbiology

High Throughput Viability Assay for Microbiology

C. T. Meyer, G. K. Lynch, D. F. Stamo, E. J. Miller, A. Chatterjee, J. M. Kralj

The paper introduces a high-throughput viability assay, GVA, that reduces time and resources compared to traditional CFU methods, enabling large-scale drug screening and discovery.

bioRxiv · Jan 4, 2023 · PreprintMicrobiology

Aminoglycosides induce a bacterial senescent state that increases antibiotic tolerance in treatment-naïve cells

C. T. Meyer, G. N. Bruni, B. Dodd, J. M. Kralj

This study shows aminoglycosides induce a bacterial senescent-like state in E. coli that increases antibiotic tolerance in untreated cells through indole secretion.

bioRxiv · Oct 4, 2021 · PreprintMicrobiology

A Consensus Framework Unifies Multi-Drug Synergy Metrics

D. J. Wooten, C. T. Meyer, V. Quaranta, C. F. Lopez

This paper presents a consensus framework to unify multi-drug synergy metrics by identifying biases in existing methods and proposing a mass-action based formalism for accurate synergy measurement.

bioRxiv · Jun 27, 2019 · PreprintPharmacology & Toxicology