NFYA promotes the anti-tumor effects of gluconeogenesis in hepatocellular carcinoma through the regulation of PCK1 expression
G. Tsujimoto, R. Ito, K. Yoshikawa, C. Ueki, N. Okada
This study shows that NFYAv2 promotes anti-tumor effects in HCC by upregulating PCK1, leading to increased ROS and energy crisis, and suggests it as a potential therapeutic target.
bioRxiv · Jun 30, 2022Cancer Biology