Extracellular matrix topography drives adrenergic to mesenchymal transition in neuroblastoma
A. Chronopoulos, C. Vemula, I. Chavez, R. Kennedy, S. Asgharzadeh, J. Park
This study shows that ECM topography promotes adrenergic to mesenchymal transition in neuroblastoma by enhancing cell-ECM interactions and activating the Rho-associated kinase pathway.
bioRxiv · Oct 10, 2023Cell Biology